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rtcB Antibody, Biotin conjugated

Rare Species
Datasheet
Code CSB-PA341647YD01EVN
Size US$166
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) rtcB Polyclonal antibody
Uniprot No.
P46850
Target Names
rtcB
Alternative Names
rtcB antibody; yhgL antibody; b3421 antibody; JW3384 antibody; RNA-splicing ligase RtcB antibody; EC 6.5.1.8 antibody; 3'-phosphate/5'-hydroxy nucleic acid ligase antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli
Immunogen
Recombinant Escherichia coli RNA-splicing ligase RtcB protein (1-408AA)
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Related Products

rtcB Antibodies

rtcB Proteins

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Target Background

Function
GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. Also acts as a DNA ligase in case of DNA damage by splicing 'dirty' DNA breaks, characterized by 3'-phosphate (or cyclic-phosphate) and 5'-hydroxy ends that cannot be sealed by classical DNA ligases.
Gene References into Functions
  1. our findings not only provide a physiological function for the RNA ligase RtcB in bacteria but highlight the reversibility of ribosome heterogeneity, a crucial but hitherto undescribed concept for translational regulation. PMID: 27789694
  2. Data show that RtcB seals broken RNAs with 3'-phosphate and 5'-OH ends. PMID: 22474365
  3. RtcB, a novel RNA ligase, can catalyze tRNA splicing and HAC1 mRNA splicing in vivo PMID: 21757685
Protein Families
RtcB family
Database Links
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